Sixers vs. Celtics NBA expert prediction and odds for Tuesday, Feb. 27 (Fade Philly)

Betting odds, pick and prediction for the Boston Celtics' matchup with the Philadelphia 76ers on Tuesday, Feb. 27.

Boston Celtics guard Jrue Holiday (4) brings the ball up.
Boston Celtics guard Jrue Holiday (4) brings the ball up. / Winslow Townson-USA TODAY Sports

Two Eastern Conference rivals will battle on Tuesday night in Boston when the Boston Celtics and Jayson Tatum host All-Star Tyrese Maxey and the Philadelphia 76ers. 

Philadelphia is playing yet another game without Joel Embiid (torn meniscus), and the team is just 7-16 in 23 games without him in the 2023-24 campaign. 

Boston isn’t elite against the spread as a home favorite, going 15-14 ATS this season, but the team is winning those games by an average margin of 13.7 points per game. 

Can Tatum and his star-filled cast pick up another win to extend their lead on the rest of the Eastern Conference? 

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Let’s break down the odds and my favorite bet for Tuesday’s matchup: 

Sixers vs. Celtics odds, spread and total

Sixers vs. Celtics how to watch

  • Date: Tuesday, Feb. 27
  • Time: 7:30 p.m. EST
  • Venue: TD Garden
  • How to watch (TV): TNT
  • Sixers record: 33-24
  • Celtics record: 45-12

Sixers vs. Celtics injury reports

Sixers injury report

  • Robert Covington – out
  • Joel Embiid – out
  • Kenneth Lofton Jr. – out
  • Terquavion Smith – out
  • KJ Martin – questionable

Celtics injury report

  • JD Davison – out
  • Drew Peterson – out

Sixers vs. Celtics key players to watch

Philadelphia 76ers

Tyrese Maxey: Over his last six games, Maxey has scored at least 22 points in each of them, pushing his season average to 25.8 points per game. The Sixers guard has struggled in two games against Boston this season (he missed one matchup), shooting a combined 17-for-42 from the field while averaging 22.5 points per game. He’ll need to be more efficient for the Sixers to have a chance to pull off the upset on Tuesday night. 

Boston Celtics

Jaylen Brown: Since the All-Star break, Jaylen Brown has been insanely efficient, shooting 7-for-12 from the field against Chicago before scoring 30 points on 13-for-24 shooting against the New York Knicks on Saturday night. Brown has taken a back seat with the Celtics adding so much talent to the roster, but he’s shooting a career-best 49.5 percent from the field this season.

The All-Star wing has struggled against the Sixers, shooting 12-for-33 in two appearances against the team this season.  

Sixers vs. Celtics prediction and pick

This is a pretty sizable number for Boston to cover, but it’s hard to trust the Sixers – even though they’ve been solid as road dogs – without Embiid. 

Boston is the best team in the NBA this season for a reason, and the team has dominated opponents at home with double-digit win after double-digit win. 

Meanwhile, the Sixers have struggled to keep pace when Embiid sits, and I question how the team matches up with Boston without the star center. 

To Philly’s credit, it held its own without Embiid or Maxey in the last meeting between these teams, losing by just six in Boston. However, it is worth noting that Kristaps Porzingis did not play for the Celtics in that game. 

When KP does play, Boston is 33-9 on the season. 

Ultimately, I can’t trust a Philly team that ranks 28th in the NBA in net rating over its last 10 games to cover the number in a tough road environment. 

Game odds refresh periodically and are subject to change.

Find Peter Dewey's NBA betting record here (futures included). You can also follow my daily plays on BetStamp here.